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Full identifier: https://w3id.org/np/RApC9zZU64P3Hf2IDjAhelbHS01p81pfFTRM87IcRWWbM/sig

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Minted in Nanopublication

Article: The induction of natural competence adapts staphylococcal metabolism to infection ResearchPaper ScholarlyWork comment approve/disapprove edit as derived nanopublication create new with same template

https://doi.org/10.1038/s41467-022-29206-7 doi:10.1038/s41467-022-29206-7 http://www.w3.org/1999/02/22-rdf-syntax-ns#type is a http://purl.org/spar/fabio/ResearchPaper research paper .

https://doi.org/10.1038/s41467-022-29206-7 doi:10.1038/s41467-022-29206-7 http://purl.org/dc/terms/title has the title (this is a literal) "The induction of natural competence adapts staphylococcal metabolism to infection" .

https://doi.org/10.1038/s41467-022-29206-7 doi:10.1038/s41467-022-29206-7 http://purl.org/dc/terms/abstract has the abstract (this is a literal) "A central question concerning natural competence is why orthologs of competence genes are conserved in non-competent bacterial species, suggesting they have a role other than in transformation. Here we show that competence induction in the human pathogen Staphylococcus aureus occurs in response to ROS and host defenses that compromise bacterial respiration during infection. Bacteria cope with reduced respiration by obtaining energy through fermentation instead. Since fermentation is energetically less efficient than respiration, the energy supply must be assured by increasing the glycolytic flux. The induction of natural competence increases the rate of glycolysis in bacteria that are unable to respire via upregulation of DNA- and glucose-uptake systems. A competent-defective mutant showed no such increase in glycolysis, which negatively affects its survival in both mouse and Galleria infection models. Natural competence foster genetic variability and provides S. aureus with additional nutritional and metabolic possibilities, allowing it to proliferate during infection." .

https://doi.org/10.1038/s41467-022-29206-7 doi:10.1038/s41467-022-29206-7 http://purl.org/dc/terms/date has the publication date (this is a literal) "2022-03-21" .

https://doi.org/10.1038/s41467-022-29206-7 doi:10.1038/s41467-022-29206-7 http://purl.org/dc/terms/isPartOf is part of the journal with ISSN http://id.crossref.org/issn/2041-1723 2041-1723 .

The journal with ISSN http://id.crossref.org/issn/2041-1723 2041-1723 http://purl.org/dc/terms/title has the title (this is a literal) "Nature Communications (Nat Commun)" .

https://doi.org/10.1038/s41467-022-29206-7 doi:10.1038/s41467-022-29206-7 http://purl.org/ontology/bibo/volume is in journal volume (this is a literal) "2022" .

https://doi.org/10.1038/s41467-022-29206-7 doi:10.1038/s41467-022-29206-7 http://purl.org/ontology/bibo/issue is in journal issue (this is a literal) "13" .

This is a local identifier minted within the nanopublication. https://w3id.org/np/RApC9zZU64.../author-list This author list This relation links a sequence/list to its element at position 1. http://www.w3.org/1999/02/22-rdf-syntax-ns#_1 has at position 1 https://orcid.org/0000-0002-1481-2996 0000-0002-1481-2996 .

https://orcid.org/0000-0002-1481-2996 0000-0002-1481-2996 http://xmlns.com/foaf/0.1/name has the name (this is a literal) "Konrad U. Förstner" .

This is a local identifier minted within the nanopublication. https://w3id.org/np/RApC9zZU64.../author-list__1 This author list This relation links a sequence/list to its element at position 2. http://www.w3.org/1999/02/22-rdf-syntax-ns#_2 has at position 2 https://orcid.org/0000-0002-7355-0674 0000-0002-7355-0674 .

https://orcid.org/0000-0002-7355-0674 0000-0002-7355-0674 http://xmlns.com/foaf/0.1/name has the name (this is a literal) "Ana Eulalio" .

This is a local identifier minted within the nanopublication. https://w3id.org/np/RApC9zZU64.../author-list__2 This author list This relation links a sequence/list to its element at position 3. http://www.w3.org/1999/02/22-rdf-syntax-ns#_3 has at position 3 https://orcid.org/0000-0002-8627-3813 0000-0002-8627-3813 .

https://orcid.org/0000-0002-8627-3813 0000-0002-8627-3813 http://xmlns.com/foaf/0.1/name has the name (this is a literal) "Daniel Lopez" .

This is a local identifier minted within the nanopublication. https://w3id.org/np/RApC9zZU64.../author-list__3 This author list This relation links a sequence/list to its element at position 4. http://www.w3.org/1999/02/22-rdf-syntax-ns#_4 has at position 4 https://orcid.org/0000-0002-6937-6394 0000-0002-6937-6394 .

https://orcid.org/0000-0002-6937-6394 0000-0002-6937-6394 http://xmlns.com/foaf/0.1/name has the name (this is a literal) "Julia García-Fernández" .

This is a local identifier minted within the nanopublication. https://w3id.org/np/RApC9zZU64.../author-list__4 This author list This relation links a sequence/list to its element at position 5. http://www.w3.org/1999/02/22-rdf-syntax-ns#_5 has at position 5 https://orcid.org/0000-0003-2705-4781 0000-0003-2705-4781 .

https://orcid.org/0000-0003-2705-4781 0000-0003-2705-4781 http://xmlns.com/foaf/0.1/name has the name (this is a literal) "Ivan C. Acosta" .

https://ror.org/0259fwx54 0259fwx54 http://xmlns.com/foaf/0.1/name has the name (this is a literal) "ZB MED – Information Centre for Life Sciences: Cologne, DE" .

https://orcid.org/0000-0002-1481-2996 0000-0002-1481-2996 http://schema.org/affiliation has the affiliation https://ror.org/0259fwx54 0259fwx54 .

This is the identifier for the assertion of this nanopublication. https://w3id.org/np/RApC9zZU64.../assertion The assertion above http://www.w3.org/ns/prov#wasAttributedTo is attributed to https://orcid.org/0009-0001-6755-0125 Johanna Sophie Mück .

This is the identifier for this whole nanopublication. https://w3id.org/np/RApC9zZU64... This nanopublication http://purl.org/dc/terms/creator is created by https://orcid.org/0009-0001-6755-0125 me (Johanna Sophie Mück) .

This is the identifier for this whole nanopublication. https://w3id.org/np/RApC9zZU64... This nanopublication http://purl.org/dc/terms/license is published under the license https://creativecommons.org/licenses/by/4.0/ Attribution 4.0 International (CC BY 4.0) .

https://orcid.org/0009-0001-6755-0125 Johanna Sophie Mück http://xmlns.com/foaf/0.1/name has the name (this is a literal) "Johanna Sophie Mück" .

This is the identifier for this whole nanopublication. https://w3id.org/np/RApC9zZU64... This nanopublication http://www.w3.org/2000/01/rdf-schema#label has the label (this is a literal) "Article: The induction of natural competence adapts staphylococcal metabolism to infection" .

This is the identifier for this whole nanopublication. https://w3id.org/np/RApC9zZU64... This nanopublication http://purl.org/nanopub/x/hasNanopubType has the type http://purl.org/spar/fabio/ScholarlyWork ScholarlyWork .

This is the identifier for this whole nanopublication. https://w3id.org/np/RApC9zZU64... This nanopublication date and time when the nanopublication was created http://purl.org/dc/terms/created was created on (this is a literal) "2025-06-25T12:53:52.514Z" .

This is the identifier for this whole nanopublication. https://w3id.org/np/RApC9zZU64... This nanopublication links to the assertion template that was used to create this nanopublication https://w3id.org/np/o/ntemplate/wasCreatedFromTemplate was created from the assertion template https://w3id.org/np/RAdU0hUGGp... RAdU0hUGGp .

This is the identifier for this whole nanopublication. https://w3id.org/np/RApC9zZU64... This nanopublication links to the provenance template that was used to create this nanopublication https://w3id.org/np/o/ntemplate/wasCreatedFromProvenanceTemplate was created from the provenance template https://w3id.org/np/RA7lSq6MuK... RA7lSq6MuK .

This is the identifier for this whole nanopublication. https://w3id.org/np/RApC9zZU64... This nanopublication links to the publication info template that was used to create this nanopublication https://w3id.org/np/o/ntemplate/wasCreatedFromPubinfoTemplate was created from the publication info template https://w3id.org/np/RA0J4vUn_d... RA0J4vUn_d .

This is the identifier for this whole nanopublication. https://w3id.org/np/RApC9zZU64... This nanopublication the nanopublication consists of an introduction of the given resource http://purl.org/nanopub/x/introduces introduces https://doi.org/10.1038/s41467-022-29206-7 doi:10.1038/s41467-022-29206-7 .

This is a local identifier minted within the nanopublication. https://w3id.org/np/RApC9zZU64.../sig sig http://purl.org/nanopub/x/hasSignatureTarget has as target This is the identifier for this whole nanopublication. https://w3id.org/np/RApC9zZU64... this nanopublication .

This is a local identifier minted within the nanopublication. https://w3id.org/np/RApC9zZU64.../sig sig http://purl.org/nanopub/x/hasAlgorithm has the algorithm (this is a literal) "RSA" .

This is a local identifier minted within the nanopublication. https://w3id.org/np/RApC9zZU64.../sig sig http://purl.org/nanopub/x/hasPublicKey has the public key (this is a literal) "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCUMHjfjDd5czAkLWmWQWazYxgcsBi7Etqzycae3evKX8LzOSYtY9pJWBW2GbkwyDwnr3BahzuYZQyF8YKl6Uj/7AebxwUMLjV6bMH9tgh/xenI0F7XzgTd6m8h01sBmV+ESFzssyiLp5bwsrWOivU+zkH+vM/oS1Vl2gaR2gbieQIDAQAB" .

This is a local identifier minted within the nanopublication. https://w3id.org/np/RApC9zZU64.../sig sig http://purl.org/nanopub/x/hasSignature has the signature (this is a literal) "gmNpra9pCyS0nQZxXGXM9JBFvUFBCjgC5ptZT74P/g47UW1oXOfGLJnQfshacGYXVb2tyIjWY0x3xK9RMbG5MOXz4dO/NnrkUBvbB57ofwlpmQGHyg2k8RX8/E5lDuPhqFFdx/6xrCe9IYvz800kRC6wdwvTL4dOHJaxey58yjw=" .

This is a local identifier minted within the nanopublication. https://w3id.org/np/RApC9zZU64.../sig sig http://purl.org/nanopub/x/signedBy is signed by https://orcid.org/0009-0001-6755-0125 Johanna Sophie Mück .

This is the identifier for this whole nanopublication. https://w3id.org/np/RApC9zZU64... This nanopublication http://purl.org/nanopub/x/wasCreatedAt was created at https://nanodash.knowledgepixels.com/ nanodash.knowledgepixels.com .

Johanna Sophie Mück, 25 Jun 2025, 12:53:52 UTC

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