assertion (explore)

assertion

Full identifier: http://purl.org/np/RAayHgg0rwyy3VekvzOBUQRTWgFievCUPaLwH4aLWhYO4#assertion

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Minted in Nanopublication

RAayHgg0rw comment approve/disapprove edit as derived nanopublication create new with same template

This is a local identifier minted within the nanopublication. http://purl.org/np/RAayHgg0rw...#association This association http://www.w3.org/2000/01/rdf-schema#label has label (this is a literal)

"Olanzapine was FDA approved for the treatment of schizophrenia and bipolar disorder only. It is an atypical antagonist of D2 and D4 receptors which determines a decrease in craving for alcohol. The DRD4 gene of dopamine presents a VNTR polymorphism, with a number of repetitions that varies from 2 to 11 which allows for the division of individuals in two subgroups: those with a number of repetitions between 2 and 6, classified as DRD4 S and those with more than 7 repetitions, classified as DRD4 L. Association studies between this variation and AUD have showed that individuals who carry the L allele exhibit greater craving after alcohol intake,50. Another study has investigated the association olanzapine-DRD4 showing that olanzapine reduces craving to the L allele carriers only, while no benefits were observed in S allele carriers."

This is a local identifier minted within the nanopublication. http://purl.org/np/RAayHgg0rw...#association This association http://www.w3.org/1999/02/22-rdf-syntax-ns#subject has drug https://identifiers.org/DRUGBANK:DB00334

DRUGBANK:DB00334

This is a local identifier minted within the nanopublication. http://purl.org/np/RAayHgg0rw...#association This association http://www.w3.org/1999/02/22-rdf-syntax-ns#object has disease http://purl.obolibrary.org/obo/DOID_1574

DOID_1574

This is a local identifier minted within the nanopublication. http://purl.org/np/RAayHgg0rw...#association This association https://w3id.org/biolink/vocab/relation has relation https://w3id.org/um/neurodkg/OffLabelIndication

An indication found in off-label drug uses

This is a local identifier minted within the nanopublication. http://purl.org/np/RAayHgg0rw...#association This association https://w3id.org/biolink/vocab/publications has publications https://pubmed.ncbi.nlm.nih.gov/29912214

pubmed.ncbi.nlm.nih.gov/29912214

This is a local identifier minted within the nanopublication. http://purl.org/np/RAayHgg0rw...#association This association http://www.w3.org/1999/02/22-rdf-syntax-ns#type has type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement association Statement .

This is a local identifier minted within the nanopublication. http://purl.org/np/RAayHgg0rw...#association This association http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate has predicate https://w3id.org/biolink/vocab/treats treats .

This is a local identifier minted within the nanopublication. http://purl.org/np/RAayHgg0rw...#association This association https://w3id.org/biolink/vocab/provided_by is provided by https://w3id.org/um/NeuroDKG NeuroDKG .

http://purl.obolibrary.org/obo/DOID_1574 DOID_1574 http://www.w3.org/1999/02/22-rdf-syntax-ns#type type https://w3id.org/biolink/vocab/Disease Disease .

This is a local identifier that was minted when the nanopublication was created. http://purl.org/np/RAayHgg0rw...#association association https://w3id.org/biolink/vocab/has_population_context has_population_context This is a local identifier that was minted when the nanopublication was created. http://purl.org/np/RAayHgg0rw...#context context .

This is a local identifier that was minted when the nanopublication was created. http://purl.org/np/RAayHgg0rw...#context context http://www.w3.org/1999/02/22-rdf-syntax-ns#type type https://w3id.org/biolink/vocab/Cohort Cohort .

This is a local identifier that was minted when the nanopublication was created. http://purl.org/np/RAayHgg0rw...#context context http://www.w3.org/2000/01/rdf-schema#label label "adults" .

https://identifiers.org/DRUGBANK:DB00334 DRUGBANK:DB00334 http://www.w3.org/1999/02/22-rdf-syntax-ns#type type https://w3id.org/biolink/vocab/Drug Drug .

This is the identifier for the assertion of this nanopublication. http://purl.org/np/RAayHgg0rw...#assertion The assertion above http://www.w3.org/ns/prov#generatedAtTime

generatedAtTime

(this is a literal)

"2021-08-26T09:18:29.198055"

(xsd:dateTime) .

This is the identifier for this whole nanopublication. http://purl.org/np/RAayHgg0rw... This nanopublication links to the assertion template that was used to create this nanopublication https://w3id.org/np/o/ntemplate/wasCreatedFromTemplate was created from the assertion template http://purl.org/np/RAhNHZw6Ur...

RAhNHZw6Ur

This is a local identifier minted within the nanopublication. http://purl.org/np/RAayHgg0rw...#sig

sig

http://purl.org/nanopub/x/hasSignatureTarget has as target This is the identifier for this whole nanopublication. http://purl.org/np/RAayHgg0rw... this nanopublication .

This is a local identifier minted within the nanopublication. http://purl.org/np/RAayHgg0rw...#sig

sig

http://purl.org/nanopub/x/hasAlgorithm has the algorithm (this is a literal)

"RSA"

This is a local identifier minted within the nanopublication. http://purl.org/np/RAayHgg0rw...#sig

sig

http://purl.org/nanopub/x/hasPublicKey has the public key (this is a literal)

"MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCamPJb4SzqpLXn//XJ5dlVfzz6QI+RPmiJTLXF/by2JR7sHMKRsCQDFsYMlq8zGHghOIkjRP9dpLZUtZzUcHt3MXiFKEPo8eGzUe9p+JXKFC8xxkJr94z2vq6IdMf71Iu1GH8SeDAKt/DgYO4zNaw8VuXvxnZRewKZSA+u8zWPVwIDAQAB"

This is a local identifier minted within the nanopublication. http://purl.org/np/RAayHgg0rw...#sig

sig

http://purl.org/nanopub/x/hasSignature has the signature (this is a literal)

"Xul0Er1OEZlq+dVjbQ0m1pCd5STdOYyyHJARC23oqe/5lhRL5V1pr6zj39fii3udiM/oFfnA67tJ2ToNRVXdbaWJ1UlSjx04RpgdSwAQUQcNm57ILUyuwyImpyCBmkQ4q1t5r9ie/+FSFHAXAtrok87vzn6Aarb0u4QuYXZyhV4="

This is the identifier for this whole nanopublication. http://purl.org/np/RAayHgg0rw...

this nanopublication

http://www.w3.org/ns/prov#generatedAtTime

generatedAtTime

(this is a literal)

"2021-08-26T09:18:29.198055"

(xsd:dateTime) .

This is the identifier for this whole nanopublication. http://purl.org/np/RAayHgg0rw...

this nanopublication

http://www.w3.org/ns/prov#wasAttributedTo

wasAttributedTo

https://orcid.org/0000-0002-7641-6446

0000-0002-7641-6446

0000-0002-7641-6446, 26 Aug 2021, 09:18:29 UTC

References

Raw

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