RAJ_wIH5Q8 (explore)

RAJ_wIH5Q8

Full identifier: http://purl.org/np/RAJ_wIH5Q8hc-PhR4wSLNcXLgaWO6Kp5wHrKZhkyOPn84

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Status

Nanopublication

RAJ_wIH5Q8 comment approve/disapprove edit as derived nanopublication create new with same template

This is a local identifier minted within the nanopublication. http://purl.org/np/RAJ_wIH5Q8...#association This association http://www.w3.org/2000/01/rdf-schema#label has label (this is a literal)

"Olanzapine was FDA approved for the treatment of schizophrenia and bipolar disorder only. It is an atypical antagonist of D2 and D4 receptors which determines a decrease in craving for alcohol. The DRD4 gene of dopamine presents a VNTR polymorphism, with a number of repetitions that varies from 2 to 11 which allows for the division of individuals in two subgroups: those with a number of repetitions between 2 and 6, classified as DRD4 S and those with more than 7 repetitions, classified as DRD4 L. Association studies between this variation and AUD have showed that individuals who carry the L allele exhibit greater craving after alcohol intake,50. Another study has investigated the association olanzapine-DRD4 showing that olanzapine reduces craving to the L allele carriers only, while no benefits were observed in S allele carriers."

This is a local identifier minted within the nanopublication. http://purl.org/np/RAJ_wIH5Q8...#association This association http://www.w3.org/1999/02/22-rdf-syntax-ns#subject has drug http://identifiers.org/drugbank/DB00334

DB00334

This is a local identifier minted within the nanopublication. http://purl.org/np/RAJ_wIH5Q8...#association This association http://www.w3.org/1999/02/22-rdf-syntax-ns#object has disease http://purl.obolibrary.org/obo/DOID_1574

DOID_1574

This is a local identifier minted within the nanopublication. http://purl.org/np/RAJ_wIH5Q8...#association This association https://w3id.org/biolink/vocab/relation has relation http://purl.obolibrary.org/obo/NCIT_C94303

NCIT_C94303

This is a local identifier minted within the nanopublication. http://purl.org/np/RAJ_wIH5Q8...#association This association https://w3id.org/biolink/vocab/publications has publications http://www.ncbi.nlm.nih.gov/pubmed/29912214

pubmed/29912214

This is a local identifier minted within the nanopublication. http://purl.org/np/RAJ_wIH5Q8...#association This association http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate has predicate https://w3id.org/biolink/vocab/treats treats .

http://identifiers.org/drugbank/DB00334

DB00334

https://w3id.org/biolink/vocab/category is a https://w3id.org/biolink/vocab/Drug Drug .

http://purl.obolibrary.org/obo/DOID_1574

DOID_1574

https://w3id.org/biolink/vocab/category is a https://w3id.org/biolink/vocab/Disease Disease .

http://identifiers.org/drugbank/DB00334 DB00334 http://www.w3.org/1999/02/22-rdf-syntax-ns#type type https://w3id.org/biolink/vocab/Drug Drug .

http://identifiers.org/drugbank/DB00334 DB00334 http://www.w3.org/2000/01/rdf-schema#label label "Olanzapine" .

http://purl.obolibrary.org/obo/DOID_1574 DOID_1574 http://www.w3.org/1999/02/22-rdf-syntax-ns#type type https://w3id.org/biolink/vocab/Disease Disease .

http://purl.obolibrary.org/obo/DOID_1574 DOID_1574 http://www.w3.org/2000/01/rdf-schema#label label "alcohol use disorder" .

This is a local identifier that was minted when the nanopublication was created. http://purl.org/np/RAJ_wIH5Q8...#association association http://www.w3.org/1999/02/22-rdf-syntax-ns#type type https://w3id.org/biolink/vocab...OrPhenotypicFeatureAssociation ChemicalToDiseaseOrPhenotypicFeatureAssociation .

This is a local identifier that was minted when the nanopublication was created. http://purl.org/np/RAJ_wIH5Q8...#association association https://w3id.org/biolink/vocab/aggregator_knowledge_source aggregator_knowledge_source https://w3id.org/biolink/infores/knowledge-collaboratory knowledge-collaboratory .

This is a local identifier that was minted when the nanopublication was created. http://purl.org/np/RAJ_wIH5Q8...#association association https://w3id.org/biolink/vocab/category category https://w3id.org/biolink/vocab...OrPhenotypicFeatureAssociation ChemicalToDiseaseOrPhenotypicFeatureAssociation .

This is a local identifier that was minted when the nanopublication was created. http://purl.org/np/RAJ_wIH5Q8...#association association https://w3id.org/biolink/vocab/has_population_context has_population_context This is a local identifier that was minted when the nanopublication was created. http://purl.org/np/RAJ_wIH5Q8...#context context .

This is a local identifier that was minted when the nanopublication was created. http://purl.org/np/RAJ_wIH5Q8...#context context http://www.w3.org/1999/02/22-rdf-syntax-ns#type type https://w3id.org/biolink/vocab/Cohort Cohort .

This is a local identifier that was minted when the nanopublication was created. http://purl.org/np/RAJ_wIH5Q8...#context context http://www.w3.org/2000/01/rdf-schema#label label "adults" .

This is a local identifier that was minted when the nanopublication was created. http://purl.org/np/RAJ_wIH5Q8...#context context https://w3id.org/biolink/vocab/category category https://w3id.org/biolink/vocab/Cohort Cohort .

This is the identifier for the assertion of this nanopublication. http://purl.org/np/RAJ_wIH5Q8...#assertion The assertion above http://www.w3.org/ns/prov#wasAttributedTo

wasAttributedTo

https://orcid.org/0000-0002-7641-6446

0000-0002-7641-6446

This is the identifier for this whole nanopublication. http://purl.org/np/RAJ_wIH5Q8... This nanopublication links to the assertion template that was used to create this nanopublication https://w3id.org/np/o/ntemplate/wasCreatedFromTemplate was created from the assertion template http://purl.org/np/RAhNHZw6Ur...

RAhNHZw6Ur

This is a local identifier minted within the nanopublication. http://purl.org/np/RAJ_wIH5Q8...#sig

sig

http://purl.org/nanopub/x/hasSignatureTarget has as target This is the identifier for this whole nanopublication. http://purl.org/np/RAJ_wIH5Q8... this nanopublication .

This is a local identifier minted within the nanopublication. http://purl.org/np/RAJ_wIH5Q8...#sig

sig

http://purl.org/nanopub/x/hasAlgorithm has the algorithm (this is a literal)

"RSA"

This is a local identifier minted within the nanopublication. http://purl.org/np/RAJ_wIH5Q8...#sig

sig

http://purl.org/nanopub/x/hasPublicKey has the public key (this is a literal)

"MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCR9fz0fKCdWOWC+pxhkQhEM/ppbdIYe5TLSdj+lJzSlv9mYBaPgrzVezSwwbmhlHBPDZa4/vHycU315BdmUGq+pXllp9+rWFfrb+kBJwhZjpG6BeyyXBsRFz4jmQVxl/ZYHilQTh/XalYzKkEAyTiEMPee4Kz61PaWOKH24CsnOQIDAQAB"

This is a local identifier minted within the nanopublication. http://purl.org/np/RAJ_wIH5Q8...#sig

sig

http://purl.org/nanopub/x/hasSignature has the signature (this is a literal)

"EZH5DT4K3l3uk6H65DHWAFQwIG+q31cWFOWWvUTRFQEbfkP87pLflbnQY7oS7uK9Y2L1/1z7o1EAR8ztBHhZBiyhtO0V2nHq+BNRb4bTQw5R6rSh7tLcxWc0nWl4tfQKmTRJFa/E1ZlhMXlourWMY1+X7ekIYjn7T3WtuTCDpnQ="

https://w3id.org/biolink/vocab/

vocab

http://purl.org/pav/version

version

(this is a literal)

"2.3.0"

This is the identifier for this whole nanopublication. http://purl.org/np/RAJ_wIH5Q8...

this nanopublication

http://www.w3.org/ns/prov#generatedAtTime

generatedAtTime

(this is a literal)

"2022-09-16T11:54:35.529379"

(xsd:dateTime) .

This is the identifier for this whole nanopublication. http://purl.org/np/RAJ_wIH5Q8...

this nanopublication

http://www.w3.org/ns/prov#wasAttributedTo

wasAttributedTo

https://orcid.org/0000-0002-1501-1082

Vincent Emonet

Vincent Emonet, 16 Sep 2022, 11:54:35 UTC

References

Raw

TriG(txt), JSON-LD(txt), N-Quads(txt), XML(txt)