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sig

Full identifier: http://purl.org/np/RA5fghTqOqBxtvOs-k77DSpG8LmFWg4EPX2sEiOvJjEbI#sig

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Minted in Nanopublication

RA5fghTqOq comment approve/disapprove edit as derived nanopublication create new with same template

This is a local identifier minted within the nanopublication. http://purl.org/np/RA5fghTqOq...#association This association http://www.w3.org/2000/01/rdf-schema#label has label (this is a literal)

"First, we estimated the change in the percentage of prescriptions for overall antipsychotics, FGA, and SGA for anxiety disorder visits from 2005 to 2013. We calculated the annual antipsychotic prescription rates as the total number of antipsychotic prescriptions divided by the total number of eligible patients with anxiety visits. The same patients are counted several times if they have several visits.We then stratified this 9-year dataset into three equal parts (2005–2007, 2008–2010, and 2011–2013) and examined the time trends in antipsychotic treatments during anxiety visits. We transformed the calendar years by subtracting 2005 from the year and dividing the results by 8. Thus, the transformed values were 0 for 2005 and 1 for 2013. The odds ratios associated with this transformed variable represent change in the odds of visits in which antipsychotic medication was prescribed across the entire study period (2005–2013). For example, an odds ratio of 2.0 denotes twice the odds that a visit included an antipsychotic at the end (2013) as compared with the start (2005) of the study period. Adjusted odds ratios (aOR) were calculated from the multivariate logistic model with adjustment for age and sex. We repeated similar analysis to examine the trends in the use of selective FGA (i.e., flupenxiol and sulpiride) and individual SGA (i.e., clozapine, risperidone, olanzapine, quetiapine, aripiprazole, and ziprasidone). (...) First-generation antipsychotics (FGA) use was more than that of second-generation antipsychotics (SGA) use in patients with anxiety disorder through the 9-year period. Sulpiride and flupentixol were the two most common FGA in the treatment of anxiety disorder. Patients with specific anxiety disorder (post-traumatic stress disorder, panic disorder/agoraphobia, generalized anxiety disorder, and obsessive-compulsive disorder), female sex, younger age (age < 65 years), comorbidity with major depression or minor depression, antidepressants concurrent use, and visits to psychiatrists, medical centers and primary care were significantly more likely to take prescribed antipsychotics"

This is a local identifier minted within the nanopublication. http://purl.org/np/RA5fghTqOq...#association This association http://www.w3.org/1999/02/22-rdf-syntax-ns#subject has drug http://identifiers.org/drugbank/DB00246

DB00246

This is a local identifier minted within the nanopublication. http://purl.org/np/RA5fghTqOq...#association This association http://www.w3.org/1999/02/22-rdf-syntax-ns#object has disease http://purl.obolibrary.org/obo/MONDO_0005618

MONDO_0005618

This is a local identifier minted within the nanopublication. http://purl.org/np/RA5fghTqOq...#association This association https://w3id.org/biolink/vocab/relation has relation http://purl.obolibrary.org/obo/NCIT_C94303

NCIT_C94303

This is a local identifier minted within the nanopublication. http://purl.org/np/RA5fghTqOq...#association This association https://w3id.org/biolink/vocab/publications has publications http://www.ncbi.nlm.nih.gov/pubmed/31077503

pubmed/31077503

This is a local identifier minted within the nanopublication. http://purl.org/np/RA5fghTqOq...#association This association http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate has predicate https://w3id.org/biolink/vocab/treats treats .

http://identifiers.org/drugbank/DB00246

DB00246

https://w3id.org/biolink/vocab/category is a https://w3id.org/biolink/vocab/Drug Drug .

http://purl.obolibrary.org/obo/MONDO_0005618

MONDO_0005618

https://w3id.org/biolink/vocab/category is a https://w3id.org/biolink/vocab/Disease Disease .

http://identifiers.org/drugbank/DB00246 DB00246 http://www.w3.org/1999/02/22-rdf-syntax-ns#type type https://w3id.org/biolink/vocab/Drug Drug .

http://identifiers.org/drugbank/DB00246 DB00246 http://www.w3.org/2000/01/rdf-schema#label label "Ziprasidone" .

http://purl.obolibrary.org/obo/MONDO_0005618 MONDO_0005618 http://www.w3.org/1999/02/22-rdf-syntax-ns#type type https://w3id.org/biolink/vocab/Disease Disease .

http://purl.obolibrary.org/obo/MONDO_0005618 MONDO_0005618 http://www.w3.org/2000/01/rdf-schema#label label "Anxiety disorder" .

This is a local identifier that was minted when the nanopublication was created. http://purl.org/np/RA5fghTqOq...#association association http://www.w3.org/1999/02/22-rdf-syntax-ns#type type https://w3id.org/biolink/vocab...OrPhenotypicFeatureAssociation ChemicalToDiseaseOrPhenotypicFeatureAssociation .

This is a local identifier that was minted when the nanopublication was created. http://purl.org/np/RA5fghTqOq...#association association https://w3id.org/biolink/vocab/aggregator_knowledge_source aggregator_knowledge_source https://w3id.org/biolink/infores/knowledge-collaboratory knowledge-collaboratory .

This is a local identifier that was minted when the nanopublication was created. http://purl.org/np/RA5fghTqOq...#association association https://w3id.org/biolink/vocab/category category https://w3id.org/biolink/vocab...OrPhenotypicFeatureAssociation ChemicalToDiseaseOrPhenotypicFeatureAssociation .

This is a local identifier that was minted when the nanopublication was created. http://purl.org/np/RA5fghTqOq...#association association https://w3id.org/biolink/vocab/has_population_context has_population_context This is a local identifier that was minted when the nanopublication was created. http://purl.org/np/RA5fghTqOq...#context context .

This is a local identifier that was minted when the nanopublication was created. http://purl.org/np/RA5fghTqOq...#context context http://www.w3.org/1999/02/22-rdf-syntax-ns#type type https://w3id.org/biolink/vocab/Cohort Cohort .

This is a local identifier that was minted when the nanopublication was created. http://purl.org/np/RA5fghTqOq...#context context http://www.w3.org/2000/01/rdf-schema#label label "Adults" .

This is a local identifier that was minted when the nanopublication was created. http://purl.org/np/RA5fghTqOq...#context context https://w3id.org/biolink/vocab/category category https://w3id.org/biolink/vocab/Cohort Cohort .

This is the identifier for the assertion of this nanopublication. http://purl.org/np/RA5fghTqOq...#assertion The assertion above http://www.w3.org/ns/prov#wasAttributedTo

wasAttributedTo

https://orcid.org/0000-0002-7641-6446

0000-0002-7641-6446

This is the identifier for this whole nanopublication. http://purl.org/np/RA5fghTqOq... This nanopublication links to the assertion template that was used to create this nanopublication https://w3id.org/np/o/ntemplate/wasCreatedFromTemplate was created from the assertion template http://purl.org/np/RAhNHZw6Ur...

RAhNHZw6Ur

This is a local identifier minted within the nanopublication. http://purl.org/np/RA5fghTqOq...#sig

sig

http://purl.org/nanopub/x/hasSignatureTarget has as target This is the identifier for this whole nanopublication. http://purl.org/np/RA5fghTqOq... this nanopublication .

This is a local identifier minted within the nanopublication. http://purl.org/np/RA5fghTqOq...#sig

sig

http://purl.org/nanopub/x/hasAlgorithm has the algorithm (this is a literal)

"RSA"

This is a local identifier minted within the nanopublication. http://purl.org/np/RA5fghTqOq...#sig

sig

http://purl.org/nanopub/x/hasPublicKey has the public key (this is a literal)

"MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCR9fz0fKCdWOWC+pxhkQhEM/ppbdIYe5TLSdj+lJzSlv9mYBaPgrzVezSwwbmhlHBPDZa4/vHycU315BdmUGq+pXllp9+rWFfrb+kBJwhZjpG6BeyyXBsRFz4jmQVxl/ZYHilQTh/XalYzKkEAyTiEMPee4Kz61PaWOKH24CsnOQIDAQAB"

This is a local identifier minted within the nanopublication. http://purl.org/np/RA5fghTqOq...#sig

sig

http://purl.org/nanopub/x/hasSignature has the signature (this is a literal)

"CBfkDJ9Nop9ZLjVzcko68A2iQGGE5z8rqxagnCiHI8SFMH0PIs52suDMXedxMr1zwS82mtzq6tEoCq1dxRxSTc9f1DL5CchipEHKztv3vhILtQfRho5NwHLZO7cBHFj7GyBMJB39XVfB74w9o12/NeMmx4Dtw20HxPDoiXOVIxo="

https://w3id.org/biolink/vocab/

vocab

http://purl.org/pav/version

version

(this is a literal)

"2.3.0"

This is the identifier for this whole nanopublication. http://purl.org/np/RA5fghTqOq...

this nanopublication

http://www.w3.org/ns/prov#generatedAtTime

generatedAtTime

(this is a literal)

"2022-09-16T11:51:15.134717"

(xsd:dateTime) .

This is the identifier for this whole nanopublication. http://purl.org/np/RA5fghTqOq...

this nanopublication

http://www.w3.org/ns/prov#wasAttributedTo

wasAttributedTo

https://orcid.org/0000-0002-1501-1082

Vincent Emonet

Vincent Emonet, 16 Sep 2022, 11:51:15 UTC

References

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