RA5NQSrZvE (explore)

RA5NQSrZvE

Full identifier: http://purl.org/np/RA5NQSrZvEs72Lng8_KQCnBrveF_3Du2xNfFJp-G82nQI

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Status

Nanopublication

RA5NQSrZvE comment approve/disapprove edit as derived nanopublication create new with same template

This is a local identifier minted within the nanopublication. http://purl.org/np/RA5NQSrZvE...#association This association http://www.w3.org/2000/01/rdf-schema#label has label (this is a literal)

"Currently, there are no FDA-approved pharmacotherapies available for CUD, though a number (eg, cannabinoids, antidepressants, anxiolytics, and glutamatergic modulators) have been proposed for off-label use. We identified 12 trials examining psychopharmacological interventions for the treatment of cannabis use disorder. Trials examined antidepressants (ie, escitalopram, fluoxetine, bupropion, nefazodone, venlafaxine, vilazodone), antipsychotics (ie, clozapine, ziprasidone), buspirone, mood stabilizers (ie, divalproex, lithium), and atomoxetine. Overall, studies found that antidepressants as a class were less effective than placebo for the achievement of abstinence (moderate SOE). There was no difference between antidepressants (moderate SOE) or buspirone (low SOE) and placebo in reducing overall cannabis use or retention in treatment. We found low strength evidence of no difference from placebo for antidepressants or buspirone on harms. Antidepressant medications did not impact secondary outcomes (low SOE). Findings for all other psychopharmacotherapies and drug/outcome combinations were either insufficient or were not identified in the current literature."

This is a local identifier minted within the nanopublication. http://purl.org/np/RA5NQSrZvE...#association This association http://www.w3.org/1999/02/22-rdf-syntax-ns#subject has drug https://identifiers.org/DRUGBANK:DB00490

DRUGBANK:DB00490

This is a local identifier minted within the nanopublication. http://purl.org/np/RA5NQSrZvE...#association This association http://www.w3.org/1999/02/22-rdf-syntax-ns#object has disease http://purl.obolibrary.org/obo/MONDO_0005689

MONDO_0005689

This is a local identifier minted within the nanopublication. http://purl.org/np/RA5NQSrZvE...#association This association https://w3id.org/biolink/vocab/relation has relation https://w3id.org/um/neurodkg/OffLabelIndication

An indication found in off-label drug uses

This is a local identifier minted within the nanopublication. http://purl.org/np/RA5NQSrZvE...#association This association https://w3id.org/biolink/vocab/publications has publications https://pubmed.ncbi.nlm.nih.gov/32227801

pubmed.ncbi.nlm.nih.gov/32227801

This is a local identifier minted within the nanopublication. http://purl.org/np/RA5NQSrZvE...#association This association http://www.w3.org/1999/02/22-rdf-syntax-ns#type has type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement association Statement .

This is a local identifier minted within the nanopublication. http://purl.org/np/RA5NQSrZvE...#association This association http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate has predicate https://w3id.org/biolink/vocab/treats treats .

This is a local identifier minted within the nanopublication. http://purl.org/np/RA5NQSrZvE...#association This association https://w3id.org/biolink/vocab/provided_by is provided by https://w3id.org/um/NeuroDKG NeuroDKG .

http://purl.obolibrary.org/obo/MONDO_0005689 MONDO_0005689 http://www.w3.org/1999/02/22-rdf-syntax-ns#type type https://w3id.org/biolink/vocab/Disease Disease .

This is a local identifier that was minted when the nanopublication was created. http://purl.org/np/RA5NQSrZvE...#association association https://w3id.org/biolink/vocab/has_population_context has_population_context This is a local identifier that was minted when the nanopublication was created. http://purl.org/np/RA5NQSrZvE...#context context .

This is a local identifier that was minted when the nanopublication was created. http://purl.org/np/RA5NQSrZvE...#context context http://www.w3.org/1999/02/22-rdf-syntax-ns#type type https://w3id.org/biolink/vocab/Cohort Cohort .

This is a local identifier that was minted when the nanopublication was created. http://purl.org/np/RA5NQSrZvE...#context context http://www.w3.org/2000/01/rdf-schema#label label "Adults" .

https://identifiers.org/DRUGBANK:DB00490 DRUGBANK:DB00490 http://www.w3.org/1999/02/22-rdf-syntax-ns#type type https://w3id.org/biolink/vocab/Drug Drug .

This is the identifier for the assertion of this nanopublication. http://purl.org/np/RA5NQSrZvE...#assertion The assertion above http://www.w3.org/ns/prov#generatedAtTime

generatedAtTime

(this is a literal)

"2021-08-24T19:10:10.436416"

(xsd:dateTime) .

This is the identifier for this whole nanopublication. http://purl.org/np/RA5NQSrZvE... This nanopublication links to the assertion template that was used to create this nanopublication https://w3id.org/np/o/ntemplate/wasCreatedFromTemplate was created from the assertion template http://purl.org/np/RAhNHZw6Ur...

RAhNHZw6Ur

This is a local identifier minted within the nanopublication. http://purl.org/np/RA5NQSrZvE...#sig

sig

http://purl.org/nanopub/x/hasSignatureTarget has as target This is the identifier for this whole nanopublication. http://purl.org/np/RA5NQSrZvE... this nanopublication .

This is a local identifier minted within the nanopublication. http://purl.org/np/RA5NQSrZvE...#sig

sig

http://purl.org/nanopub/x/hasAlgorithm has the algorithm (this is a literal)

"RSA"

This is a local identifier minted within the nanopublication. http://purl.org/np/RA5NQSrZvE...#sig

sig

http://purl.org/nanopub/x/hasPublicKey has the public key (this is a literal)

"MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCamPJb4SzqpLXn//XJ5dlVfzz6QI+RPmiJTLXF/by2JR7sHMKRsCQDFsYMlq8zGHghOIkjRP9dpLZUtZzUcHt3MXiFKEPo8eGzUe9p+JXKFC8xxkJr94z2vq6IdMf71Iu1GH8SeDAKt/DgYO4zNaw8VuXvxnZRewKZSA+u8zWPVwIDAQAB"

This is a local identifier minted within the nanopublication. http://purl.org/np/RA5NQSrZvE...#sig

sig

http://purl.org/nanopub/x/hasSignature has the signature (this is a literal)

"T0ViHnEmtZCTy/i5NoSX+3SxYVis6jPekbD+y2h6YN3ahmCErJRY+cfSZ/u7SiC6JHzUzG/fwXY5Vss1G710tkeVRi1NkZJaUH9DfI++mf2Y0c3nEInzAmMgUDgAppuuojiitcL40y5XwgO0vMkqte64QUyzVXZEwAhNCdPDmd8="

This is the identifier for this whole nanopublication. http://purl.org/np/RA5NQSrZvE...

this nanopublication

http://www.w3.org/ns/prov#generatedAtTime

generatedAtTime

(this is a literal)

"2021-08-24T19:10:10.436416"

(xsd:dateTime) .

This is the identifier for this whole nanopublication. http://purl.org/np/RA5NQSrZvE...

this nanopublication

http://www.w3.org/ns/prov#wasAttributedTo

wasAttributedTo

https://orcid.org/0000-0002-7641-6446

0000-0002-7641-6446

0000-0002-7641-6446, 24 Aug 2021, 19:10:10 UTC

References

Raw

TriG(txt), JSON-LD(txt), N-Quads(txt), XML(txt)