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STAYAHEAD_AF

Full identifier: https://w3id.org/np/RAVLW4m4-aEKD5vnkvzf-hpqsQJQOi7Dw3DXGFqesX9hc/STAYAHEAD_AF

Assigned to 2 classes:

Minted in Nanopublication

 STAYAHEAD AlphaFold-2 Mutational Variant Dataset Dataset FAIRDigitalObject comment approve/disapprove edit as derived nanopublication create new with same template

This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../STAYAHEAD_AF STAYAHEAD_AF https://w3id.org/fdof/ontology#hasMetadata has its metadata in This is the identifier for this whole nanopublication. https://w3id.org/np/RAVLW4m4-a... this nanopublication .
This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../STAYAHEAD_AF STAYAHEAD_AF http://purl.org/dc/terms/hasVersion has version (this is a literal) "v1.0" .
This is the identifier for this whole nanopublication. https://w3id.org/np/RAVLW4m4-a... This nanopublication date and time when the nanopublication was created http://purl.org/dc/terms/created was created on (this is a literal) "2025-07-11T14:14:10.950Z" (xsd:dateTime) .
This is the identifier for this whole nanopublication. https://w3id.org/np/RAVLW4m4-a... This nanopublication links to the assertion template that was used to create this nanopublication https://w3id.org/np/o/ntemplate/wasCreatedFromTemplate was created from the assertion template https://w3id.org/np/RAc1AU2eoL... RAc1AU2eoL .
This is the identifier for this whole nanopublication. https://w3id.org/np/RAVLW4m4-a... This nanopublication links to the provenance template that was used to create this nanopublication https://w3id.org/np/o/ntemplate/wasCreatedFromProvenanceTemplate was created from the provenance template https://w3id.org/np/RA7lSq6MuK... RA7lSq6MuK .
This is the identifier for this whole nanopublication. https://w3id.org/np/RAVLW4m4-a... This nanopublication links to the publication info template that was used to create this nanopublication https://w3id.org/np/o/ntemplate/wasCreatedFromPubinfoTemplate was created from the publication info template https://w3id.org/np/RA0J4vUn_d... RA0J4vUn_d .
This is the identifier for this whole nanopublication. https://w3id.org/np/RAVLW4m4-a... This nanopublication links to the publication info template that was used to create this nanopublication https://w3id.org/np/o/ntemplate/wasCreatedFromPubinfoTemplate was created from the publication info template https://w3id.org/np/RAukAcWHRD... RAukAcWHRD .
This is the identifier for this whole nanopublication. https://w3id.org/np/RAVLW4m4-a... This nanopublication the nanopublication consists of an introduction of the given resource http://purl.org/nanopub/x/introduces introduces This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../STAYAHEAD_AF STAYAHEAD_AF .
This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../sig sig http://purl.org/nanopub/x/hasSignatureTarget has as target This is the identifier for this whole nanopublication. https://w3id.org/np/RAVLW4m4-a... this nanopublication .
This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../sig sig http://purl.org/nanopub/x/hasAlgorithm has the algorithm (this is a literal) "RSA" .

Max van den Boom, 11 Jul 2025, 14:14:10 UTC

References

Nanopublication Part Subject Predicate Object Published By Published On
links a nanopublication to its assertion http://www.nanopub.org/nschema#hasAssertion assertion
STAYAHEAD_AF
Max van den Boom
2025-07-11T14:14:10.950Z
links a nanopublication to its assertion http://www.nanopub.org/nschema#hasAssertion assertion
STAYAHEAD_AF
Max van den Boom
2025-07-11T14:14:10.950Z
links a nanopublication to its assertion http://www.nanopub.org/nschema#hasAssertion assertion
STAYAHEAD_AF
STAYAHEAD AlphaFold-2 Mutational Variant Dataset
Max van den Boom
2025-07-11T14:14:10.950Z
links a nanopublication to its assertion http://www.nanopub.org/nschema#hasAssertion assertion
STAYAHEAD_AF
Max van den Boom
2025-07-11T14:14:10.950Z
links a nanopublication to its assertion http://www.nanopub.org/nschema#hasAssertion assertion
STAYAHEAD_AF
Max van den Boom
2025-07-11T14:14:10.950Z
links a nanopublication to its assertion http://www.nanopub.org/nschema#hasAssertion assertion
STAYAHEAD_AF
The resource centers on the RBD of the ancestral Wuhan-Hu-1 spike protein and includes a systematically generated set of all possible single-point missense variants (3,705 in total). All variants are annotated with structural descriptors derived from AlphaFold-2 predicted structures and augmented with sequence-based biophysical predictors such as disorder, flexibility, and amyloid aggregation propensity from the Bio2Byte suite. To complement structural predictions, empirical measurements of ACE2 binding affinity and surface expression levels were integrated for each 1-step variant, based on deep mutational scanning (DMS) data published by Starr et al. This pairing of theoretical and experimental annotations provides a foundation for analyzing structure–function relationships across the spike mutational landscape and supports downstream applications in protein modeling, variant characterization, and structure-guided surveillance.
Max van den Boom
2025-07-11T14:14:10.950Z
links a nanopublication to its assertion http://www.nanopub.org/nschema#hasAssertion assertion
STAYAHEAD_AF
Max van den Boom
2025-07-11T14:14:10.950Z
links a nanopublication to its assertion http://www.nanopub.org/nschema#hasAssertion assertion
STAYAHEAD_AF
Max van den Boom
2025-07-11T14:14:10.950Z
links a nanopublication to its assertion http://www.nanopub.org/nschema#hasAssertion assertion
STAYAHEAD_AF
Max van den Boom
2025-07-11T14:14:10.950Z
links a nanopublication to its assertion http://www.nanopub.org/nschema#hasAssertion assertion
STAYAHEAD_AF
Max van den Boom
2025-07-11T14:14:10.950Z

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