STAYAHEAD AlphaFold-2 Mutational Variant Dataset (explore)

STAYAHEAD AlphaFold-2 Mutational Variant Dataset

Full identifier: https://w3id.org/np/RAVLW4m4-aEKD5vnkvzf-hpqsQJQOi7Dw3DXGFqesX9hc/STAYAHEAD_AF

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Minted in Nanopublication

STAYAHEAD AlphaFold-2 Mutational Variant Dataset Dataset FAIRDigitalObject comment approve/disapprove edit as derived nanopublication create new with same template

This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../STAYAHEAD_AF STAYAHEAD_AF http://www.w3.org/1999/02/22-rdf-syntax-ns#type is a https://w3id.org/fdof/ontology#FAIRDigitalObject FAIR Digital Object (FDO) .

This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../STAYAHEAD_AF STAYAHEAD_AF http://www.w3.org/2000/01/rdf-schema#label has the label (this is a literal) "STAYAHEAD AlphaFold-2 Mutational Variant Dataset" .

This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../STAYAHEAD_AF STAYAHEAD_AF http://www.w3.org/2000/01/rdf-schema#comment has description (this is a literal) "The resource centers on the RBD of the ancestral Wuhan-Hu-1 spike protein and includes a systematically generated set of all possible single-point missense variants (3,705 in total). All variants are annotated with structural descriptors derived from AlphaFold-2 predicted structures and augmented with sequence-based biophysical predictors such as disorder, flexibility, and amyloid aggregation propensity from the Bio2Byte suite. To complement structural predictions, empirical measurements of ACE2 binding affinity and surface expression levels were integrated for each 1-step variant, based on deep mutational scanning (DMS) data published by Starr et al. This pairing of theoretical and experimental annotations provides a foundation for analyzing structure–function relationships across the spike mutational landscape and supports downstream applications in protein modeling, variant characterization, and structure-guided surveillance." .

This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../STAYAHEAD_AF STAYAHEAD_AF https://w3id.org/fdof/ontology#hasMetadata has its metadata in This is the identifier for this whole nanopublication. https://w3id.org/np/RAVLW4m4-a... this nanopublication .

https://osf.io/9tj6b 9tj6b https://w3id.org/fdof/ontology#materializes is a concrete materialization of This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../STAYAHEAD_AF STAYAHEAD_AF .

https://osf.io/9tj6b 9tj6b https://w3id.org/fdof/ontology#hasEncodingFormat has the format https://www.iana.org/assignments/media-types/text/csv csv .

https://osf.io/9tj6b 9tj6b http://purl.org/dc/terms/license has data usage license http://purl.org/np/RAQ__sGdY_...#CC-BY-4.0 CC BY 4.0 | Attribution 4.0 International .

https://osf.io/9tj6b 9tj6b https://www.w3.org/ns/dcat#accessURL has access URL https://osf.io/9tj6b 9tj6b .

https://osf.io/9tj6b 9tj6b http://purl.org/dc/terms/issued was published (this is a literal) "2024" .

This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../STAYAHEAD_AF STAYAHEAD_AF http://purl.org/dc/terms/creator has creator https://orcid.org/0009-0004-2188-0817 Max van den Boom .

This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../STAYAHEAD_AF STAYAHEAD_AF http://purl.org/dc/terms/contributor has contributor https://orcid.org/0000-0001-8888-635X Erik Schultes .

This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../STAYAHEAD_AF STAYAHEAD_AF https://www.w3.org/ns/dcat#contactPoint has contact point (this is a literal) "info@health-holland.com" .

This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../STAYAHEAD_AF STAYAHEAD_AF http://purl.org/dc/terms/language uses language https://www.omg.org/spec/LCC/Languages/LaISO639-1-LanguageCodes/en en .

This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../STAYAHEAD_AF STAYAHEAD_AF http://purl.org/dc/terms/subject has domain http://aims.fao.org/aos/agrovoc/c_4318 Life Science .

This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../STAYAHEAD_AF STAYAHEAD_AF http://purl.org/dc/terms/publisher has publisher https://ror.org/056cwr036 056cwr036 .

This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../STAYAHEAD_AF STAYAHEAD_AF http://purl.org/dc/terms/hasVersion has version (this is a literal) "v1.0" .

This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../STAYAHEAD_AF STAYAHEAD_AF https://schema.org/funder has funder https://ror.org/056cwr036 056cwr036 .

This is the identifier for the assertion of this nanopublication. https://w3id.org/np/RAVLW4m4-a.../assertion The assertion above http://www.w3.org/ns/prov#wasAttributedTo is attributed to https://orcid.org/0009-0004-2188-0817 Max van den Boom .

This is the identifier for this whole nanopublication. https://w3id.org/np/RAVLW4m4-a... This nanopublication http://purl.org/dc/terms/creator is created by https://orcid.org/0009-0004-2188-0817 me (Max van den Boom) .

This is the identifier for this whole nanopublication. https://w3id.org/np/RAVLW4m4-a... This nanopublication http://purl.org/dc/terms/license is published under the license https://creativecommons.org/licenses/by/4.0/ Attribution 4.0 International (CC BY 4.0) .

https://orcid.org/0009-0004-2188-0817 Max van den Boom http://xmlns.com/foaf/0.1/name has the name (this is a literal) "Max van den Boom" .

This is the identifier for this whole nanopublication. https://w3id.org/np/RAVLW4m4-a... This nanopublication date and time when the nanopublication was created http://purl.org/dc/terms/created was created on (this is a literal) "2025-07-11T14:14:10.950Z" (xsd:dateTime) .

This is the identifier for this whole nanopublication. https://w3id.org/np/RAVLW4m4-a... This nanopublication links to the assertion template that was used to create this nanopublication https://w3id.org/np/o/ntemplate/wasCreatedFromTemplate was created from the assertion template https://w3id.org/np/RAc1AU2eoL... RAc1AU2eoL .

This is the identifier for this whole nanopublication. https://w3id.org/np/RAVLW4m4-a... This nanopublication links to the provenance template that was used to create this nanopublication https://w3id.org/np/o/ntemplate/wasCreatedFromProvenanceTemplate was created from the provenance template https://w3id.org/np/RA7lSq6MuK... RA7lSq6MuK .

This is the identifier for this whole nanopublication. https://w3id.org/np/RAVLW4m4-a... This nanopublication links to the publication info template that was used to create this nanopublication https://w3id.org/np/o/ntemplate/wasCreatedFromPubinfoTemplate was created from the publication info template https://w3id.org/np/RA0J4vUn_d... RA0J4vUn_d .

This is the identifier for this whole nanopublication. https://w3id.org/np/RAVLW4m4-a... This nanopublication the nanopublication consists of an introduction of the given resource http://purl.org/nanopub/x/introduces introduces This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../STAYAHEAD_AF STAYAHEAD_AF .

http://purl.org/np/RAQ__sGdY_...#CC-BY-4.0 CC BY 4.0 | Attribution 4.0 International https://w3id.org/np/o/ntemplate/hasLabelFromApi has the label from an API (this is a literal) "CC BY 4.0 | Attribution 4.0 International - Using this licence you are free to share and adapt the resource but you must ..." .

This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../sig sig http://purl.org/nanopub/x/hasSignatureTarget has as target This is the identifier for this whole nanopublication. https://w3id.org/np/RAVLW4m4-a... this nanopublication .

This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../sig sig http://purl.org/nanopub/x/hasAlgorithm has the algorithm (this is a literal) "RSA" .

This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../sig sig http://purl.org/nanopub/x/hasPublicKey has the public key (this is a literal) "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCwNmDuHNCGRTNccDpvK2x9Hdbgac9Z2e7nF9KxqArfCGNMkK5UcEBeNv6Lx1mgUVXAL6cZERLL1Fssu7cLZEdaAUiPTkCLSNWWLbBNTTlVWR9+2dP00VrRToaqDYhZBo3E6Psc+GfOyDNJJ7n7r2vVsDiLMsUmQCHeLiX4pXukfwIDAQAB" .

This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../sig sig http://purl.org/nanopub/x/hasSignature has the signature (this is a literal) "gykUctN8nkBBr9d68apeIgXdcT/FwC5n3BbeW+52947il7ollGLS8IpiGMJOupnghiDoiMwvfscC/OkAgEASTGDt3ezQLIX3qEXW1hUTM6EfKtseYKeOvzKjQpSKEwV7W/K4FDp7yVKd3ZHOY38zXpHuah6mJur2wxOPk/V3I+U=" .

This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../sig sig http://purl.org/nanopub/x/signedBy is signed by https://orcid.org/0009-0004-2188-0817 Max van den Boom .

This is the identifier for this whole nanopublication. https://w3id.org/np/RAVLW4m4-a... This nanopublication http://purl.org/nanopub/x/wasCreatedAt was created at https://nanodash.knowledgepixels.com/ nanodash.knowledgepixels.com .

Max van den Boom, 11 Jul 2025, 14:14:10 UTC

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