Nanopublication: RAYpxq5rXv
Full identifier: http://purl.org/np/RAYpxq5rXvcOhvm_3iwhWAc7I3-UFzibuft686cFeaIC0
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAYpxq5rXv...#association
This association
http://www.w3.org/2000/01/rdf-schema#label
has label
(this is a literal)
"therapy with lipid altering agents should be only one component of multiple risk factor intervention in individuals at significantly increased risk for atherosclerotic vascular disease due to hypercholesterolemia drug therapy is indicated as an adjunct to diet when the response to a diet restricted in saturated fat and cholesterol and other nonpharmacologic measures alone has been inadequate ezetimibe tablets are an inhibitor of intestinal cholesterol and related phytosterol absorption indicated as an adjunct to diet to reduce elevated total c ldl c apo b and non hdl c in patients with primary hyperlipidemia alone or in combination with an hmg coa reductase inhibitor statin 1 1 reduce elevated total c ldl c apo b and non hdl c in patients with mixed hyperlipidemia in combination with fenofibrate 1 1 reduce elevated total c and ldl c in patients with homozygous familial hypercholesterolemia hofh in combination with atorvastatin or simvastatin 1 2 reduce elevated sitosterol and campesterol in patients with homozygous sitosterolemia phytosterolemia 1 3 limitations of use 1 4 the effect of ezetimibe tablets on cardiovascular morbidity and mortality has not been determined ezetimibe tablets have not been studied in fredrickson type i iii iv and v dyslipidemias monotherapy ezetimibe tablets administered alone are indicated as adjunctive therapy to diet for the reduction of elevated total cholesterol total c low density lipoprotein cholesterol ldl c apolipoprotein b apo b and non high density lipoprotein cholesterol non hdl c in patients with primary heterozygous familial and non familial hyperlipidemia combination therapy with hmg coa reductase inhibitors statins ezetimibe tablets administered in combination with a 3 hydroxy 3 methylglutaryl coenzyme a hmg coa reductase inhibitor statin is indicated as adjunctive therapy to diet for the reduction of elevated total c ldl c apo b and non hdl c in patients with primary heterozygous familial and non familial hyperlipidemia combination therapy with fenofibrate ezetimibe tablets administered in combination with fenofibrate are indicated as adjunctive therapy to diet for the reduction of elevated total c ldl c apo b and non hdl c in adult patients with mixed hyperlipidemia ezetimibe tablets administered in combination with fenofibrate are indicated as adjunctive therapy to diet for the reduction of elevated total c ldl c apo b and non hdl c in adult patients with mixed hyperlipidemia the combination of ezetimibe tablets and atorvastatin or simvastatin is indicated for the reduction of elevated total c and ldl c levels in patients with hofh as an adjunct to other lipid lowering treatments e g ldl apheresis or if such treatments are unavailable ezetimibe tablets are indicated as adjunctive therapy to diet for the reduction of elevated sitosterol and campesterol levels in patients with homozygous familial sitosterolemia the effect of ezetimibe tablets on cardiovascular morbidity and mortality has not been determined ezetimibe tablets have not been studied in fredrickson type i iii iv and v dyslipidemias"
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAYpxq5rXv...#association
This association
http://www.w3.org/1999/02/22-rdf-syntax-ns#subject
has drug
https://identifiers.org/drugbank:DB00973
drugbank:DB00973
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAYpxq5rXv...#association
This association
http://www.w3.org/1999/02/22-rdf-syntax-ns#object
has disease
http://purl.obolibrary.org/obo/DOID_0090019
DOID_0090019
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAYpxq5rXv...#association
This association
https://w3id.org/biolink/vocab/relation
has relation
https://w3id.org/um/neurodkg/SymptomaticReliefIndication
An indication for only managing the symptoms of the condition
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAYpxq5rXv...#association
This association
https://w3id.org/biolink/vocab/association_type
has BioLink type
https://w3id.org/biolink/vocab...OrPhenotypicFeatureAssociation
ChemicalToDiseaseOrPhenotypicFeatureAssociation
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAYpxq5rXv...#association
This association
http://www.w3.org/1999/02/22-rdf-syntax-ns#type
has type
http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement
association Statement
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAYpxq5rXv...#association
This association
http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate
has predicate
https://w3id.org/biolink/vocab/treats
treats
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAYpxq5rXv...#association
This association
https://w3id.org/biolink/vocab/provided_by
is provided by
https://w3id.org/um/NeuroDKG
NeuroDKG
.
This is the identifier for the assertion of this nanopublication.
http://purl.org/np/RAYpxq5rXv...#assertion
The assertion above
http://www.w3.org/ns/prov#wasAttributedTo
is attributed to
https://orcid.org/0000-0002-1468-3557
me (Leoni Bücken)
.
This is the identifier for this whole nanopublication.
http://purl.org/np/RAYpxq5rXv...
This nanopublication
http://purl.org/dc/terms/creator
is created by
https://orcid.org/0000-0002-1468-3557
me (Leoni Bücken)
.
This is the identifier for this whole nanopublication.
http://purl.org/np/RAYpxq5rXv...
This nanopublication
date and time when the nanopublication was created
http://purl.org/dc/terms/created
was created on
(this is a literal)
"2021-07-03T11:44:22.258+02:00"
.
This is the identifier for this whole nanopublication.
http://purl.org/np/RAYpxq5rXv...
This nanopublication
links to the assertion template that was used to create this nanopublication
https://w3id.org/np/o/ntemplate/wasCreatedFromTemplate
was created from the assertion template
http://purl.org/np/RAManV5GZI...
RAManV5GZI
.
This is the identifier for this whole nanopublication.
http://purl.org/np/RAYpxq5rXv...
This nanopublication
links to the provenance template that was used to create this nanopublication
https://w3id.org/np/o/ntemplate/wasCreatedFromProvenanceTemplate
was created from the provenance template
http://purl.org/np/RANwQa4ICW...
RANwQa4ICW
.
This is the identifier for this whole nanopublication.
http://purl.org/np/RAYpxq5rXv...
This nanopublication
links to the publication info template that was used to create this nanopublication
https://w3id.org/np/o/ntemplate/wasCreatedFromPubinfoTemplate
was created from the publication info template
http://purl.org/np/RAA2MfqdBC...
RAA2MfqdBC
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAYpxq5rXv...#sig
sig
http://purl.org/nanopub/x/hasSignatureTarget
has as target
This is the identifier for this whole nanopublication.
http://purl.org/np/RAYpxq5rXv...
this nanopublication
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAYpxq5rXv...#sig
sig
http://purl.org/nanopub/x/hasAlgorithm
has the algorithm
(this is a literal)
"RSA"
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAYpxq5rXv...#sig
sig
http://purl.org/nanopub/x/hasPublicKey
has the public key
(this is a literal)
"MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCODwZkXojpEKwk7Ldj2oPPfCstvqrcpgCaTLo235K7ht9C7E1GCkLvUuL2b4VWXJTcZx/hxgDauR8hUeYq/lS6tfTL9yFZsnfl+PWYDyz7vv6N+wJVx2LL8bO6ntCjcOzvW2t2WUeF12Sb6b3I6uOYP0N8iQKts1WasY/yEYKAHQIDAQAB"
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAYpxq5rXv...#sig
sig
http://purl.org/nanopub/x/hasSignature
has the signature
(this is a literal)
"K4RgGojoaZEv6cVy9cRyL7/yu5Agl/x5aPTFWNSHeeMaTEJ094bLybVaSC8owx7ZOI8ENw1iq4yWH1D9BGYk+xLN+VGqc22tc2Br4SwK/CwFQdFUDYZe9EbL0WirGZwEv0cqlkH1H4K39rGfzjLZtQctj2hR7wEyvhzuifpFDUE="
.