@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix this: <http://purl.org/np/RAbGN2VRlquUswu_klRBdWvArjO9B6p6MZPE2BtOM5rpQ> .
@prefix sub: <http://purl.org/np/RAbGN2VRlquUswu_klRBdWvArjO9B6p6MZPE2BtOM5rpQ#> .
@prefix schema: <https://schema.org/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix orcid: <https://orcid.org/> .
@prefix nkg: <https://w3id.org/neurodkg/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix npx: <http://purl.org/nanopub/x/> .
@prefix prov: <http://www.w3.org/ns/prov#> .

<http://purl.org/np/RAbGN2VRlquUswu_klRBdWvArjO9B6p6MZPE2BtOM5rpQ> a np:Nanopublication;
  np:hasAssertion sub:assertion;
  np:hasProvenance sub:provenance;
  np:hasPublicationInfo sub:pubinfo;
  dcterms:created "2021-04-08T18:00:00.000+01:00"^^xsd:dateTime;
  dcterms:creator orcid:0000-0001-7769-4272;
  npx:supercedes <http://purl.org/np/RAMDYfA4Ndzrvu1GRyMKa5UbJgIgDf2WGO3hIdW7gtUgQ> .

sub:assertion a nt:AssertionTemplate;
  rdfs:label "Defining a target group for drug therapy";
  nt:hasStatement sub:st05a, sub:st05b, sub:st05c, sub:st05d, sub:st05e;
  prov:wasAttributedTo orcid:0000-0001-7769-4272 .

sub:audienceType a nt:LiteralPlaceholder;
  rdfs:label "has the target group (eg. adult, pregnant)" .

sub:condition a nt:LocalResource;
  rdfs:label " The condition for target population" .

sub:conditionText a nt:LiteralPlaceholder;
  rdfs:label "describe the condition here" .

sub:conditionURI a nt:GuidedChoicePlaceholder;
  rdfs:label "define the condition for target population using DOID";
  nt:possibleValuesFromApi "http://data.bioontology.org/search?pagesize=20&apikey=fd451bec-eacd-4519-b972-90fb6c7007cb&include_properties=false&ontologies=DOID&q=" .

sub:disease a nt:GuidedChoicePlaceholder;
  rdfs:label "has disease using DOID";
  nt:possibleValuesFromApi "http://data.bioontology.org/search?pagesize=20&apikey=fd451bec-eacd-4519-b972-90fb6c7007cb&include_properties=false&ontologies=DOID&q=" .

sub:drug a nt:UriPlaceholder;
  rdfs:label "add a Drugbank identifier here (e.g. DB00295)";
  nt:hasPrefix "http://identifiers.org/drugbank/";
  nt:hasPrefixLabel " has the drug";
  nt:hasRegex "[A-Z]{2}\\d{5}" .

sub:indi_type a nt:GuidedChoicePlaceholder;
  rdfs:label "add the indication type for medical therapy";
  nt:possibleValue schema:ApprovedIndication, schema:PreventionIndication, schema:TreatmentIndication,
    nkg:AdjunctiveTherapy, nkg:SymptomaticReliefIndication .

sub:maxAge a nt:LiteralPlaceholder;
  rdfs:label "Audiences defined by a person's maximum age.";
  nt:hasRegex "[0-9]*" .

sub:medtherapy a nt:LocalResource;
  rdfs:label "This medical therapy " .

sub:minAge a nt:LiteralPlaceholder;
  rdfs:label "Audiences defined by a person's minimum age.";
  nt:hasRegex "[0-9]*" .

sub:quote a nt:LocalResource;
  rdfs:label "This quoted text" .

sub:quotedtext a nt:LiteralPlaceholder;
  rdfs:label "quote the supporting text here" .

sub:source a nt:UriPlaceholder;
  rdfs:label "add the URL to the source (e.g. DailyMed URL) of the quoted text here" .

sub:st05a a nt:OptionalStatement, nt:RepeatableStatement;
  rdf:object sub:audienceType;
  rdf:predicate schema:audienceType;
  rdf:subject sub:targetpop;
  nt:statementOrder 6 .

sub:st05b a nt:OptionalStatement;
  rdf:object sub:minAge;
  rdf:predicate schema:requiredMinAge;
  rdf:subject sub:targetpop;
  nt:statementOrder 7 .

sub:st05c a nt:OptionalStatement;
  rdf:object sub:maxAge;
  rdf:predicate schema:requiredMaxAge;
  rdf:subject sub:targetpop;
  nt:statementOrder 8 .

sub:st05d a nt:OptionalStatement, nt:RepeatableStatement;
  rdf:object sub:conditionURI;
  rdf:predicate schema:healthCondition;
  rdf:subject sub:targetpop;
  nt:statementOrder 9 .

sub:st05e a nt:OptionalStatement, nt:RepeatableStatement;
  rdf:object sub:symptom;
  rdf:predicate schema:signOrSymptom;
  rdf:subject sub:conditionURI;
  nt:statementOrder 10 .

sub:symptom a nt:GuidedChoicePlaceholder;
  rdfs:label "target biomedical entity from Translator NameResolution API";
  nt:possibleValuesFromApi "https://name-resolution-sri.renci.org/lookup?limit=10&string=" .

sub:targetpop a nt:UriPlaceholder;
  rdfs:label "The target group for a drug therapy" .

owl:sameAs rdfs:label "corresponds to the term" .

prov:quotedText rdfs:label "claims" .

prov:wasDerivedFrom rdfs:label "was derived from" .

prov:wasQuotedFrom rdfs:label "was quoted from" .

schema:ApprovedIndication rdfs:label "An indication for a medical therapy that has been formally specified or approved by a regulatory body." .

schema:PreventionIndication rdfs:label "An indication for preventing an underlying condition, symptom, etc." .

schema:TreatmentIndication rdfs:label "An indication for treating an underlying condition." .

schema:audienceType rdfs:label "has type" .

schema:healthCondition rdfs:label "has health condition" .

schema:requiredMaxAge rdfs:label "has max age" .

schema:requiredMinAge rdfs:label "has min age" .

schema:signOrSymptom rdfs:label "has symptom" .

nkg:SymptomaticReliefIndication rdfs:label "An indication for only managing the symptoms of the condition" .

sub:sig npx:hasAlgorithm "RSA";
  npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCOqbrPT5RmzxsvRXGHZSAXPzeRLt9ogiosL3tcPKC0g5J8B1577lnJ3oVKSfD80lgPJdr9K671RazGL/mkZ/yu/uCNqne07Q9jd6OIAEi3fldiVfGK8ZDh43rGWRuG+BlvbZ1lZRFrWsURTKTpMgh0C6vJFRIMkWH6ImbZC5JbbQIDAQAB";
  npx:hasSignature "KvP7VF+bOy40k2uWOYm+go8DKMnTufGXzA/EWD/Sir1ECeePVzvC6hYZmDkZLEezchIEcnUpEMX9lGhOgX3n+acUv1hG/wThcbHqUYFo5gt7KGhzJNAfOMoYBs1OCDKq5q0GNibVkJnjI4dmheq9wPQgJLfhliwuwIN3JGUTEsk=";
  npx:hasSignatureTarget <http://purl.org/np/RAbGN2VRlquUswu_klRBdWvArjO9B6p6MZPE2BtOM5rpQ> .