@prefix ns1: .
@prefix this: .
@prefix sub: .
@prefix xsd: .
@prefix rdf: .
@prefix rdfs: .
@prefix prov: .
@prefix np: .
@prefix orcid: .
@prefix nt: .
@prefix npx: .
@prefix schema: .
@prefix nkg: .
@prefix owl: .
a np:Nanopublication;
np:hasAssertion sub:assertion;
np:hasProvenance sub:provenance;
np:hasPublicationInfo sub:pubinfo;
ns1:created "2021-02-10T18:00:00.000+01:00"^^xsd:dateTime;
ns1:creator orcid:0000-0001-7769-4272;
npx:supercedes .
sub:assertion a nt:AssertionTemplate;
rdfs:label "Defining a drug indication with its medical context";
nt:hasStatement sub:st00, sub:st01, sub:st02, sub:st03, sub:st04, sub:st05;
prov:wasAttributedTo orcid:0000-0001-7769-4272 .
sub:audienceType a nt:LiteralPlaceholder;
rdfs:label "has the target group (eg. adult, pregnant)" .
sub:condition a nt:LocalResource;
rdfs:label " The condition for target population" .
sub:conditionText a nt:LiteralPlaceholder;
rdfs:label "describe the condition here" .
sub:conditionURI a nt:GuidedChoicePlaceholder;
rdfs:label "define the condition for target population using DOID";
nt:possibleValuesFromApi "http://data.bioontology.org/search?pagesize=20&apikey=fd451bec-eacd-4519-b972-90fb6c7007cb&include_properties=false&ontologies=DOID&q=" .
sub:disease a nt:GuidedChoicePlaceholder;
rdfs:label "has disease using DOID";
nt:possibleValuesFromApi "http://data.bioontology.org/search?pagesize=20&apikey=fd451bec-eacd-4519-b972-90fb6c7007cb&include_properties=false&ontologies=DOID&q=" .
sub:drug a nt:UriPlaceholder;
rdfs:label "add a Drugbank identifier here (e.g. DB00295)";
nt:hasPrefix "http://identifiers.org/drugbank/";
nt:hasPrefixLabel " has the drug";
nt:hasRegex "[A-Z]{2}\\d{5}" .
sub:indi_type a nt:GuidedChoicePlaceholder;
rdfs:label "add the indication type for medical therapy";
nt:possibleValue schema:ApprovedIndication, schema:PreventionIndication, schema:TreatmentIndication,
nkg:AdjunctiveTherapy, nkg:SymptomaticReliefIndication .
sub:maxAge a nt:LiteralPlaceholder;
rdfs:label "Audiences defined by a person's maximum age.";
nt:hasRegex "[0-9]*" .
sub:medtherapy a nt:LocalResource;
rdfs:label "This medical therapy " .
sub:minAge a nt:LiteralPlaceholder;
rdfs:label "Audiences defined by a person's minimum age.";
nt:hasRegex "[0-9]*" .
sub:quote a nt:LocalResource;
rdfs:label "This quoted text" .
sub:quotedtext a nt:LiteralPlaceholder;
rdfs:label "quote the supporting text here" .
sub:source a nt:UriPlaceholder;
rdfs:label "add the URL to the source (e.g. DailyMed URL) of the quoted text here" .
sub:st00 a nt:GroupedStatement, nt:OptionalStatement;
nt:hasStatement sub:st00a, sub:st00b, sub:st00c;
nt:statementOrder 1 .
sub:st00a a rdf:Statement;
rdf:object sub:quote;
rdf:predicate prov:wasDerivedFrom;
rdf:subject sub:medtherapy;
nt:statementOrder 1 .
sub:st00b a rdf:Statement;
rdf:object sub:quotedtext;
rdf:predicate prov:value;
rdf:subject sub:quote;
nt:statementOrder 2 .
sub:st00c a rdf:Statement;
rdf:object sub:source;
rdf:predicate prov:wasQuotedFrom;
rdf:subject sub:quote;
nt:statementOrder 3 .
sub:st01 a rdf:Statement;
rdf:object sub:drug;
rdf:predicate schema:drug;
rdf:subject sub:medtherapy;
nt:statementOrder 2 .
sub:st02 a rdf:Statement;
rdf:object sub:medtherapy;
rdf:predicate schema:possibleTreatment;
rdf:subject sub:disease;
nt:statementOrder 3 .
sub:st03 a rdf:Statement;
rdf:object sub:indi_type;
rdf:predicate nkg:indicationType;
rdf:subject sub:medtherapy;
nt:statementOrder 4 .
sub:st04 a rdf:Statement;
rdf:object sub:targetpop;
rdf:predicate schema:targetPopulation;
rdf:subject sub:medtherapy;
nt:statementOrder 5 .
sub:st05 a nt:GroupedStatement, nt:OptionalStatement, nt:RepeatableStatement;
nt:hasStatement sub:st05a, sub:st05b, sub:st05c, sub:st05d, sub:st05e;
nt:statementOrder 6 .
sub:st05a a rdf:Statement;
rdf:object sub:audienceType;
rdf:predicate schema:audienceType;
rdf:subject sub:targetpop;
nt:statementOrder 1 .
sub:st05b a rdf:Statement;
rdf:object sub:minAge;
rdf:predicate schema:requiredMinAge;
rdf:subject sub:targetpop;
nt:statementOrder 2 .
sub:st05c a rdf:Statement;
rdf:object sub:maxAge;
rdf:predicate schema:requiredMaxAge;
rdf:subject sub:targetpop;
nt:statementOrder 3 .
sub:st05d a nt:RepeatableStatement;
rdf:object sub:conditionURI;
rdf:predicate schema:healthCondition;
rdf:subject sub:targetpop;
nt:statementOrder 4 .
sub:st05e a nt:RepeatableStatement;
rdf:object sub:symptom;
rdf:predicate schema:signOrSymptom;
rdf:subject sub:conditionURI;
nt:statementOrder 5 .
sub:symptom a nt:GuidedChoicePlaceholder;
rdfs:label "target biomedical entity from Translator NameResolution API";
nt:possibleValuesFromApi "https://name-resolution-sri.renci.org/lookup?limit=10&string=" .
sub:targetpop a nt:LocalResource;
rdfs:label "The target group" .
owl:sameAs rdfs:label "corresponds to the term" .
prov:quotedText rdfs:label "claims" .
prov:wasDerivedFrom rdfs:label "was derived from" .
prov:wasQuotedFrom rdfs:label "was quoted from" .
schema:ApprovedIndication rdfs:label "An indication for a medical therapy that has been formally specified or approved by a regulatory body." .
schema:PreventionIndication rdfs:label "An indication for preventing an underlying condition, symptom, etc." .
schema:TreatmentIndication rdfs:label "An indication for treating an underlying condition." .
schema:audienceType rdfs:label "has type" .
schema:healthCondition rdfs:label "has health condition" .
schema:requiredMaxAge rdfs:label "has max age" .
schema:requiredMinAge rdfs:label "has min age" .
schema:signOrSymptom rdfs:label "has symptom" .
nkg:SymptomaticReliefIndication rdfs:label "An indication for only managing the symptoms of the condition" .
sub:sig npx:hasAlgorithm "RSA";
npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCR9fz0fKCdWOWC+pxhkQhEM/ppbdIYe5TLSdj+lJzSlv9mYBaPgrzVezSwwbmhlHBPDZa4/vHycU315BdmUGq+pXllp9+rWFfrb+kBJwhZjpG6BeyyXBsRFz4jmQVxl/ZYHilQTh/XalYzKkEAyTiEMPee4Kz61PaWOKH24CsnOQIDAQAB";
npx:hasSignature "fMS0jq5DhjfG+Uoc1BY62tG2z/o2AfTjb+q5woFQW+nleuH2zCwQwUNRRPQu1O9XnIN/uuENL8VnwAdFjih7ji22ag1CuaHf125ehSBNfbqK8kesSuul8wBew8Xi9QCOFoyw6LeruOvvwKm5dYb7m4+fjwPlkc9xTB9dsJHzJiw=";
npx:hasSignatureTarget .